Title Gaussian mixture model of heart rate variability.
Author Costa, Tommaso; Boccignone, Giuseppe; Ferraro, Mario
Journal PLoS One Publication Year/Month 2012
PMID 22666386 PMCID PMC3364278
Affiliation 1.Dipartimento di Psicologia, Universita di Torino, Torino, Italy. tommaso.costa@unito.it.

Heart rate variability (HRV) is an important measure of sympathetic and parasympathetic functions of the autonomic nervous system and a key indicator of cardiovascular condition. This paper proposes a novel method to investigate HRV, namely by modelling it as a linear combination of Gaussians. Results show that three Gaussians are enough to describe the stationary statistics of heart variability and to provide a straightforward interpretation of the HRV power spectrum. Comparisons have been made also with synthetic data generated from different physiologically based models showing the plausibility of the Gaussian mixture parameters.

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