| Title | Alteration of autonomic blood pressure control during hemodialysis in peripheral vascular disease patients. | ||
| Author | Titapiccolo, Jasmine Ion; Cerutti, Sergio; Garzotto, Francesco; Cruz, Dinna; Moissl, Ulrich; Tetta, Ciro; Signorini, Maria G; Ronco, Claudio; Ferrario, Manuela | ||
| Journal | Annu Int Conf IEEE Eng Med Biol Soc | Publication Year/Month | 2011 |
| PMID | 22255586 | PMCID | -N/A- |
| Affiliation | 1.Politecnico di Milano, Department of Bioengineering, P zza Leonardo daVinci 32, 20133 Milano, Italy. jasmine.ion@mail.polimi.it. | ||
Blood pressure (BP) response to volume depletion induced by hemodialysis (HD) treatment may be important to understand the pathophysiology of the increased mortality in HD patients with vascular calcification. In the present study a comparison between end stage renal disease (ESRD) patients affected by peripheral vascular disease (PVD) and ESRD patients without PVD was performed. Continuous blood pressure was recorded at the beginning and at the end of HD. BP and heart rate variability (HRV) were analyzed to quantify the autonomic nervous system regulation of heart beat and peripheral resistance. PVD patients showed an increase of pulse pressure (PP) during HD, an altered autonomic peripheral control, a lower sympathetic activity, with respect to ESRD patients without PVD.