| Title | Human rhinovirus C--associated severe pneumonia in a neonate. | ||
| Author | Broberg, Eeva; Niemela, Jussi; Lahti, Elina; Hyypia, Timo; Ruuskanen, Olli; Waris, Matti | ||
| Journal | J Clin Virol | Publication Year/Month | 2011-May |
| PMID | 21342784 | PMCID | PMC7172304 |
| Affiliation | 1.Department of Virology, University of Turku, Kiinamyllynkatu 13, FI-20520 Turku, Finland. | ||
We present a case of severe pneumonia, associated with a prolonged infection by a species C rhinovirus (HRV) in a 3-week old neonate. HRV RNA was identified in nasal and nasopharyngeal secretions, bronchoalveolar lavage and bronchial specimens, stool and urine, collected from the patient during a one-month period. No other viral or bacterial agents were detected. Sequence analysis of two regions of the viral genome, amplified directly from the clinical specimens revealed a novel HRV-C variant. These observations highlight the occurrence of severe neonatal infections caused by HRVs and the need of rapid viral diagnostics for their detection.