| Title | Heart rate dynamics in temporal lobe epilepsy-A long-term follow-up study. | ||
| Author | Suorsa, Eija; Korpelainen, Juha T; Ansakorpi, Hanna; Huikuri, Heikki V; Suorsa, Ville; Myllyla, Vilho V; Isojarvi, Jouko I T | ||
| Journal | Epilepsy Res | Publication Year/Month | 2011-Jan |
| PMID | 21093218 | PMCID | -N/A- |
| Affiliation | 1.Department of Neurology, University of Oulu, Oulu, Finland. eronkain@paju.oulu.fi. | ||
The aim of the present study was to prospectively evaluate long-term changes in interictal heart rate variability (HRV) in patients with temporal lobe epilepsy (TLE). A 24-h ECG was recorded at baseline and after a mean follow-up of 6.1 years in 18 patients with refractory TLE and 18 patients with well-controlled TLE. After the follow-up, the Poincare components SD(1) (p=0.039) and SD(2) (p=0.001) were decreased in patients with refractory TLE compared to baseline, whereas in patients with well-controlled TLE no changes (p>0.05) in HR variability were observed. The reduction in HRV seems to be progressive in patients with chronic refractory TLE with recurrent seizures.