Title Effects of music therapy on psychological symptoms and heart rate variability in patients with dementia. A pilot study.
Author Raglio, Alfredo; Oasi, Osmano; Gianotti, Marta; Manzoni, Veronica; Bolis, Silvia; Ubezio, Maria C; Gentile, Simona; Villani, Daniele; Stramba-Badiale, Marco
Journal Curr Aging Sci Publication Year/Month 2010-Dec
PMID 20735342 PMCID -N/A-
Affiliation 1.Sospiro Foundation, Piazza Liberta, 2 - 26048 Sospiro, Cremona, Italy. raglioa@tin.it.

We assessed the effects of music therapy (MT) on behavioral and psychological symptoms (BPSD) in dementia associated with changes in physiological parameters, as heart rate (HR) and heart rate variability (HRV). Twenty subjects were randomly assigned to MT treatment or standard care; all patients underwent neuropsychological assessment and ECG Holter recordings before and after the 15-week treatment. The treatment included 30 MT sessions. Depression significantly decreased (p=0.021) in the MT group. PNN50 improved in 50% patients of the MT group, but in none of the control group (p=0.013). MT may improve symptoms of depression and increase HRV in demented patients.

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