Title Spectral analysis of heart rate variability for early prediction of pregnancy-induced hypertension.
Author Pal, G K; Shyma, P; Habeebullah, S; Shyjus, P; Pal, Pravati
Journal Clin Exp Hypertens Publication Year/Month 2009-Jun
PMID 19811361 PMCID -N/A-
Affiliation 1.Department of Physiology, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry - 605 006, India. gopalpravati@sify.com.

The early prediction of pregnancy-induced hypertension (PIH), a common morbid disorder of pregnancy is unsatisfactory. Therefore, in the present study we have investigated the role of spectral analysis of heart rate variability (HRV) in the early prediction of PIH. Spectral analysis of HRV was performed in three groups of subjects (Group I: normal pregnant women; Group II: pregnant women with risk factors, but did not develop PIH; Group III: pregnant women with risk factors and developed PIH). It was observed that the LF-HF ratio, the most sensitive indicator of sympathovagal balance, was significantly high (p < 0.01) since early pregnancy in group III compared to other groups, which was significantly correlated with heart rate and blood pressure. It was suggested that the predictive knowledge of sympathovagal imbalance should be utilized in designing the prevention and management of PIH.

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