| Title | [Non-linear variability of maternal cardiac rhythm and prognostication of pathological pregnancy outcome]. | ||
| Author | Kleshchegonov, S A; Kan'kovska, O I | ||
| Journal | Vestn Ross Akad Med Nauk | Publication Year/Month | 2009 |
| PMID | 19711523 | PMCID | -N/A- |
Some indices of non-linear heart rate variability (HRV) in pregnant women were assessed with reference to early diagnosis of gestational pathology. It was shown that simultaneous decrease of approximate entropy (ApEn) as low as 1.96 and increase of detrended fluctuation analysis (DFA) parameter of more than 0.85 are associated with the development of severe complications of pregnancy in 75% of the cases examined between 16 and 23 weeks. The informative value of isolated DFA index is twice that of ApEn. Combined use of DFA and ApEn indices of non-linear HRV ensures a 12 times higher probability of correct prognosis of obstetric pathology compared with theoretical (apriori) probability.