| Title | A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers. | ||
| Author | Higgins, P G; Barrow, G I; Tyrrell, D A | ||
| Journal | Antiviral Res | Publication Year/Month | 1990-Dec |
| PMID | 1965113 | PMCID | PMC7134172 |
| Affiliation | 1.MRC Common Cold Unit, Harvard Hospital, Salisbury, Wiltshire, U.K. | ||
In a double-blind placebo controlled trial intranasal NPC 567, a bradykinin antagonist, failed to alleviate the symptoms of experimental rhinovirus colds. Indeed, there was evidence that the drug enhanced the symptoms although no irritant effect was detected on the uninfected nasal mucosa.