Title Impaired cardiac autonomic nervous control after cardiac bypass surgery for congenital heart disease.
Author McGlone, Laura; Patel, Neil; Young, David; Danton, Mark D
Journal Interact Cardiovasc Thorac Surg Publication Year/Month 2009-Aug
PMID 19454415 PMCID -N/A-
Affiliation 1.Princess Royal Maternity Hospital, Alexandra Parade, Glasgow, Scotland, UK. mcglonelaura@hotmail.com.

We undertook a study to describe changes in heart rate variability (HRV) postoperatively in children undergoing cardiac bypass surgery for congenital heart disease (CHD). HRV was recorded for a 1-h period preoperatively and a 24-h period postoperatively in 20 children with CHD. We found a highly significant reduction in HRV in both time and frequency domain indices compared to preoperative values, which was sustained throughout the 24-h study period. There was a negative correlation between both time and frequency domain HRV measurements and length of cardiac bypass. HRV is reduced postoperatively and correlates with cardiac bypass time. Length of cardiac bypass time may be one mechanism whereby HRV is reduced following surgery.

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