Cardiac arrhythmia is frequently detected in patients with mitral valve prolapse (MVP) and improper autonomic tone is considered the etiology. Heart rate turbulence (HRT) and heart rate variability (HRV) are methods assessed for autonomic dysfunction. To evaluate whether the number of ventricular premature contractions (VPCs) is influenced by HRT or HRV in patients with MVP. Holter monitoring for the number of VPCs and correlation analysis with HRT and HRV was performed. There were 31% and 3% with abnormal turbulence onset (TO) and turbulence slope (TS) values in totally 68 patients. No significant correlation is found between the number of VPCs and HRT, HRV parameters. In analysis the relationship between HRT and HRV parameters, TS has higher correlation with HRV than TO values, particular in time-domain.