| Title | [Rhinovirus and acute bronchiolitis in young infants]. | ||
| Author | Pitrez, Paulo M C; Stein, Renato T; Stuermer, Larissa; Macedo, Izolete S; Schmitt, Virginia M; Jones, Marcus H; Arruda, Eurico | ||
| Journal | J Pediatr (Rio J) | Publication Year/Month | 2005-Sep-Oct |
| PMID | 16247546 | PMCID | -N/A- |
| Affiliation | 1.Departamento de Pediatria, Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil. pmpitrez@pucrs.br. | ||
OBJECTIVE: To determine the prevalence of rhinovirus infection in hospitalized young infants with acute bronchiolitis. METHODS: Hospitalized children with acute bronchiolitis admitted to the Hospital Sao Lucas/PUCRS between May and September 2002 were selected prospectively. Nasopharyngeal samples were assayed for respiratory syncytial virus, parainfluenza, influenza and adenovirus by immunofluorescence. For rhinovirus test a reverse transcription-polymerase chain reaction for picornavirus was used, followed by hybridization with rhinovirus specific probes. RESULTS: Forty-five patients were selected for the study. The median age of the subjects studied was 2 months. Positive samples for respiratory viruses were found in 35/45 (77.8%) subjects and 7/35 (20%) patients had dual infection. Respiratory syncytial virus was detected in 33/35 (94%) cases. Rhinovirus was detected in 6/35 patients (17%). CONCLUSIONS: Rhinovirus was the second most common agent detected in nasal secretions from young infants hospitalized with acute bronchiolitis.